In the case of any drug like Tamilfu we are talking about big pharmaceuticals so it is not a good example for small companies. Any small business that wants to release a new product for human consumption that includes new drugs is going to have to spend a lot of money to show it is safe. Open peer-review is just a way to ensure that there is no cheating. IP is protected by patents and that is another issue. Of course a small company faces many problems if they want to release something like a health product and in most cases would have to work with a larger company to finance the approval checks. That is a whole set of problems but I don't think that open-peer review makes it worse. In cases of alternative medicines where companies use pee-review to support their claims of effectiveness open peer-review is a good way to separate the products that really work and are safe from the pseudoscience where they try to use low quality or corrupt peer-review to sell their product.

I think there are very few trade secrets these days. Regulations mean that almost everything that goes into a drug or food product needs to be revealed. Only the way they are prepared and partly the quantities can be hidden, but these are not hard to replicate. Patents help protect but it is common to see new products copied where patents dont apply. This is a problem for small companies but it is not changed by open peer-review.

You ask who is going to pay. Peer-review is done for free by scientists on the basis of mutual benefit and career advancement. There is no reason why open peer-review should be any different. When peer-review is directly paid for it becomes suspect.

You also mention anonymity. open peer-review can be anonymous either for author or reviewer so that is a separate issue. It is an interesting one, but not what this essay is about.

As for who will pay for indefinite online access, it is not very expensive. I run viXra out of my own pocket and I am far from rich. arXiv is much more expensive to run but it is less than one academics library budget to Elsevier for their journal subscriptions. Web based archives can be run by research centres using off-the-shelf software and their existing servers. It is not a big expense.

I hope this answers some of your questions

Dear Philip,

Many thanks for the actual essay, the deep analysis of the Science at the beginning of the Information age, relevant ideas, best offers and Open VixRa. Open Society and Open Science - a reliable way to the future of Humanity.

Let's keep The Peace, save The World and The Earth together! New Generation says all inhabitants spacecraft named "Earth": Time to start the path.

Thank FQXi that brings together people for "brainstorming" on very important topics of modern Humanity and modern Science!

I invite you to comment on and appreciate my ideas.

High regard,

Vladimir

Philip,

This was a good and needed essay. Clearly it tapped into much and well-warranted frustration in our community, lifting it to the top of the ratings. I agree with your well-structured, basic critique of the existing system. For example, the bias against independent researchers impedes their expression and careers and prevents others from benefiting from their work (even if some smaller portion of it would be valuable, compared to that of traditional academics. If ...) ViXra has commendably helped fill a gap in access.

However, I don't think that traditional peer review needs to be so radically overhauled. There is a place for it. I think one good way to at least reduce the power of bias is to promote and enlarge blind peer review, where the name and the affiliation of the author is hidden from the reviewers. (Well, maybe "peer" isn't the best word since the contributor may not really be a "peer", but this is the context we normally refer to.) Sure, reviewers have some clues to guess with, but at least they will not be sure and can more easily direct to the merits of the piece (writers will of course need subtle ways to avoid implying identity and background.) Yes, reviewers will still perhaps have some bias against the very act of having submitted as BPR. Yes, the Editor/s will still know, and so on. Yet I think this is helpful. Some journals already offer BPR, and I'd like to see more of it. Your thoughts would be appreciated. Thanks again for a great essay, with an impact enhanced by your own unfortunate experiences tilting against academic windmills. If enough of us ride together with purpose and direction, the result will not be quixotic.

    Dear Phillip

    Your clear and distinctive proposition addressed one of the key problems and pointed to the simple solution of the self-similar matrix of the age of problems... But as you may witness, in order to justify and preserve themselves, non-living systems - institutions - are not about solving but rather maintaining and creating problems... Small patches are sometime accepted, especially when those patches make things even more complicated or more expensive, but simplicity, logic and mathematical rigour become a part of some romantic past. As written by the Nobel Prize winner, Leon Lederman, the age of reaching for the truth purely by thinking of the phenomenon, drawing geometry on sand, the time of Tales, Pythagoras or Archimedes is an issue of some distant and in scientific terms more primitive past... Nowadays, says Lederman the truth is revealed by machines... In other words, exclude the creative thinking and switch on the accelerator... and if you cannot afford it, tuff luck, you are too primitive to be a scientist...

    You may have been noticed that non-living systems - institutions (states, religions, corporations, institutionalised science...) - favour all which is unnecessary, artificial, unhealthy, uniformed, obedient, destructive, lethal, non-reproductive, and non-alive. On the other hand, living necessities like reasoning, individual intelligence, sexuality, reproductive organs, natural food, healing plants, freedom, life as such... are "legitimately" stigmatized, neglected, rejected, forbidden, tortured or executed... On the universal scale this self-similar matrix can be recognized as Tanatos versus Eros... On a scale of a body, it is virus versus cell.

    I am sure you remember the OPERA neutrino experiment anomaly. Using very precise methods, during the time between 2009 and 2011, the OPERA team performed successive measurements in which the result remained unchanged. As specifically noted in the conclusion of their article published on http://arxiv.org/abs/1109.4897 they felt obliged to inform the scientific community of their unexplainable results. Shortly after the publication, CERN sends the division, significantly named ICARUS, which announces the discovery of insufficiently pressed cable :)... Entirely uncritically, the "argument" was immediately accepted by "scientific community", the anomaly was dead, the Standard model survived and CERN kept its throne... Consequently, the "rebellious" heads of the leaders of the OPERA team have silently fallen...

    Then I read that the similar, though less significant results were measured and overlooked by some other, earlier experiments, performed by less powerful accelerators...

    By putting my trust in the equality symbol of mathematics and the universal validity of its principles, I took a coffee break, a piece of paper and the pen, and calculate the implicit result obtained by OPERA team. Therefore, I consider the self-proclaimed "Temple of the science" not only irrelevant but intentionally false. At full conscience and responsibility I declare the OPERA experiment anomaly denial as being one of the biggest scientific frauds of our modern history. The only accepted argument which can refute the stated is proving that the speed of light is not equal to EM wavelength over its wave-time or that mathematic and geometry, being considered as primitive, aren't tools for the truth.

    And of course, it is published on your "insignificant" viXra. Take its marginalisation, neglecting, ignoring and rejection as a compliment :)

    I invite you to open review my nonaligned essay The Arrow of Time.

    Regards,

    andrej

    Dear Gibbs,

    I found your essay much absorbing. It held my interest through out.

    I have attempted to rate you accordingly to keep the pace of your leadership but the system has not justified that. I am contacting the FQXI to resolve.

    I want you to read my article STRIKING A BALANCE BETWEEN TECHNOLOGY AND ECOSYSTEM on this link http://fqxi.org/community/forum/topic/2020

    I have a model that is similar with your ideology. I expect your comment and rating at the end.

    Wishing you the very best in this competition.

    Regards

    Gbenga

    Philip,

    Open Peer Review with Business Incubator

    I support your essay strongly, with the additional requirement of "qualified" peer reviewers in diverse fields of expertise.

    I have written to an NSF program called Synergy and provided a whitepaper to test their interest in funding a cloud based tool. The social networking tool would be available to everyone to create broad enterprise based upon individual concepts being developed in a public forum.

    "If you are going to listen, do something." ~Thomas Dunn

    Hi Philip,

    At first I though, is this really that important for steering the future.

    On second thought ... Yes it is very important. Open peer review can help with the problem of being locked into what we know for certain (peer reviewed) that just isn't so.

    I am reminded of the recent Nobel Prize speech in physics where the recipient encouraged that physicists should publicly agree on string theory when in private they are not sure about string theory. This strikes me as an unethical way to enhance the public image of physics and physicists and enhances the propagation of what isn't so.

    Thanks for your essay.

    Don Limuti

    Hi Philip,

    Your position is clearly stated, and you argue for it in detail. One concern, however, is

    whether implementation of knowledge isn't a bigger problem than defects in the process of acquisition of new knowledge. At the end of the third paragraph, you state, "We have the intellectual capacity to figure these things out and steer the right course, yet we fail." Very true. But isn't the greater problem at the stage of steering rather than at the stage of figuring things out? Georgina Parry suggests this in the exchange with you on May 1. I think Sabine Hossenfelder in her essay especially emphasizes that deficiencies in implementation are at the present time more serious than problems with the acquisition of knowledge. Surely you have identified an important problem, but there might be even more serious problems at other places in the many processes of acquiring, distributing, and utilizing knowledge.

    Laurence Hitterdale

      Eckart wrote: "Does global warming really deserve much more attention than poisoning the environment with radioactive and other waste?"

      As I have written elsewhere, Global Warming is the least of our problems. See also The Politics and Ethics of the Hall Weather Machine . I'll go even farther here and claim that nanotechnology, in the form of advanced medical nanobots, will make radiation and chemical poisoning equally irrelevant in the lifetime of some readers.

      That is generally a good thing, but if humanity has the power to easily solve global warming (while significantly increasing the standard of living for everyone on this planet), that kind of power can also cause some major damage.

      Because of that possible abuse of power, we must become a multi-world species (one of the imperatives that I covered briefly in my essay Three Crucial Technologies ).

      Eckart also wrote: "Agreeing with outsiders like Nobel and Shannon rather than Einstein and Bourbaki".

      That perception is new to me. Google results are:

      "Outsiders"

      Alfred Nobel: 4,830,000 hits

      Claude Shannon 1,720,000 hits

      "Insiders"

      Albert Einstein 119,000,000 hits (Ok, he's an insider :-) )

      Nicolas Bourbaki 802,000 hits (as far as the internet is concerned, that collective is noise)

      And for some humbling perspective on how important science and math are in the eyes of the world:

      Beatles 356,000,000 hits

      Lady Gaga 230,000,000 hits

      Dear Philip,

      Thanks for submitting your well-written, and well-thought-out essay. I especially appreciated your list of biases. Have you ever considered coding any of these biases or other logical fallacies into RDF/OWL? My hope is that such a system would detect articles with excessive bias and logical error (and save me the trouble of reading them). The Semantic Web will help enhance our thinking (and reduce our biases) in other areas (e.g. law, medicine), not just scientific discovery, is one of the Three Crucial Technologies ) that I mention in my essay (feel free to critique it).

      I do wonder if the "IKEA effect" has more to it than just bias. As Richard Feynman said, "What I cannot create, I do not understand." OK, IKEA uses low-strength particle board instead of wood, but their design engineering and supply chain methods are fantastic.

      You say that we are illogical because of bias, but then you don't ask the next question. What is the evolutionary advantage of bias in thought? Maybe I should leave it as an exercise for the reader, but the short answer is, "Because for a large enough percentage of the time, it works." Those of our ancestors who did not employ bias in their reason died before they could become our ancestors.

      I understand that the current publishing system could use some improvement, and I appreciate your hard work in establishing a more open publishing venue. But, not being an academic (and most of the world are not academics) I'm not sure that it really matters. People who reify scientific ideas into products (like Steve Jobs), or people who incentivize (or disincentivize) socially beneficial work (like the governments who make the laws of a democratic capitalist country) matter a lot more than we do. And while it is humbling for us scientists and engineers, it turns out that most discoveries usually pop up in more than once place near the same time. We really don't matter that much. :-(

      You mentioned the importance and desirability of "carefully considered logic." Well, yes, and I do call for it in my essay, but we must remember that logic has it's limits (as proven by Godel, and recognized by anyone who has done any work with Descriptive Logics that do inferences over Semantic Web data. The upshot is that knowledge is not enough. Even wisdom may not be enough, if you don't have the advanced nanotechnology needed to feed the hungry (and heal the obese) without overloading our ecosystem. And even advanced nanotechnology can't save us from large K/T asteroids, nuclear war, and the like--for that we need a space-faring civilization.

      Fixing the peer review of today's journal publishing system would be a good thing, but it won't save the world.

        Laurence. I think the key to the implementation is getting the peer-review right. Peer-review is not part of the stage of "figuring things out" It is the stage between figuring things out and implementing the right solutions. If the peer-review is done right and is clear and open enough to convince people that it is right, then the implementation will follow. Of course none of the stages are easy and all could do with some attention, but my point is that the peer-review is the one that is being done most wrong and is the one in most need of a rethink.

        @Laurence

        "...defects in the process of acquisition of new knowledge" "ephasizes that deficiencies in implementation are at the present time more serious than problems with the acquisition of knowledge"

        So perhaps broad development in skills related to Common Sense coupled with an Open Peer Review forum with related Business Incubation may be a stronger solution.

        Common Sense = Self-esteem (shared social group skills) logic predicting consequences

        The skills of predicting consequences within the complexities of skills shared by a social group (physicists for instance) seems to be an act of developing new relationships to support new applications.

        Open Peer Review with Business Incubation has the potential of creating new sustainable outcomes.

        I completely agree that the time has come for open peer review, Philip. The system we have is ridiculous and counterproductive. I do wonder whether some expert curation is important to make sure the best papers emerge from the general noise, but I largely agree with everything you say.

        While I think open peer review is an excellent idea, I'm not sure it's enough to save the world. It would certainly help, for example, if we understood the global climate better than we do. But I don't think better science will convince climate change deniers that we need to take more action. I'm afraid that our hardest problems may not be scientific, but political; that they may be driven by conflict over ends and interests that scientific research alone cannot resolve.

        Best,

        Rober de Neufville

        Robert de Neufville

          @Tihamer @Robert @Philip

          Would you like to collaborate on implementing an Actual system, and not just engage in mental exercise? These essay submissions are unimportant unless acted upon.

          From my perspective, you each are talking about different parts of the same system.

          1) broad and diverse open forum limited to unrestricted research

          2) software automation to make phases of development obvious and provide supporting tools to grow each phase of development

          3) motivational structures built into the system to drive development into implementation

          4) crowd-sourcing tools made available to fund phases of development. This is especially interesting because then after seeding an NSF proposal it can evolve in parallel diverse directions to seed other developments not ever first considered in the original NSF proposal. So NSF would become a one of the many crowd-sourcing funding agencies.

          5) Training tools for skills can be made available to everyone to acquire social group related skills. Where each development project that evolves within the open peer review forum involves diverse specialties. To share communication skills with the group each person will need to familiarize themselves with the jargon and rudimentary relationships that are common to each participant. These related skills can be made available via online courses (many of which are currently free).

          6) A system of equitable participation is developed to track the total involvement and contributions of each peer development group that evolves from the open peer review group. In this way when monetary gains occur, each person can be equitably be compensated.

          7) .........

          http://jamesbdunn2.blogspot.com/2014/05/open-peer-review-to-support-synergy-of.html

          I can go on, but I hope this is enough information to create a perspective of an open online tool where open peer review transitions into open peer development.

          Tihamer's concepts for supporting his three points of steering the future involved rhetoric (the expert use of language) to define perspectives of commonly relatable situations that resulted in:

          1. Develop physical tools that give atomically precise control over bulk matter,

          2. Multiply the size, diversity, and hardiness of Earth's biosphere (by transplanting it elsewhere),

          3. Develop tools that help us think better.

          I myself have attempted to do mind mappings for all of these. I'm guessing I'm not unique. So why aren't we doing something about it together?

          Robert, you seem to be relating how a person's political connections and influences (i.e. perspectives and relationships) drive the support systems for any development. Political tools are built in applying the same structural foundations but different environment of applications for common sense.

          Common Sense = Self-esteem (sharing of social group skills) logic predicting consequences

          So politics is based in understanding and applying emotional skills logically connected to social skills, to manipulate broad systems of human efforts toward a desired set of outcomes.

          Nothing we know is absolute, except for one thing; "Something Exists". Everything else is built from relative systems of perspectives and supporting relationships. We cannot see or perceive everything relative to a perspective, so sometimes other unseen influences become dominant and our perspective no longer is completely valid.

          I challenge you to find one perspective other than "Something Exists" that is Absolutely True always in every time frame and every dimensional consideration. If you do, then you have found a characteristic of quantum causality.

          Our brains live in what others outside this forum would consider an illusion. We use repeatable observations that result from identified consequences that provide a higher probability of success than random. Bias is based in broad perceived likelihood for success relative to the total systems of involved with a consideration.

          So no two people are going to share the same biases.

          The Open Peer Review process inclusive of other areas is important.

          Expertise in one area of consideration can be almost completely unrelated to another perspective being considered.

          Open Peer Review that causes people of like interests to mutually develop common skills to share in a development has the potential to drive broad economic developments, that fund ever growing numbers of significant developments that we currently cannot fund with our present system of peer review.

          What do you think? Productive collaboration?

          You can contact me at the below url so you do not expose your email address to spam harvesters.

          http://www.ua-kits.com/frontpage/index.php/contact-us/

            Oh, I inadvertently repeated myself - and thanks for answering my original statement of the same issues (more elaborately here, but no big deal.) Keep up the good work.

            James, I'm glad you are thinking about how to implement this. One reason why I have not tried to do anything like this myself is that to succeed any project needs the backing of academics. Otherwise you will not get the right people to do the peer-review for the reasons I mentioned in the essay. Everyone's opinion should count but most research is still done withing the professional academic world and they need to be behind it. I dont want to invest my time and effort in something unless I know there is good backing.

            Things are slow. http://episciences.org/ looked good a year ago and still could work but I don't know why progress on that has been so slow. There is also open peer-review opening up at http://www.researchgate.net/ but I think they will be vulnerable to take over like Mendeley was. http://www.philica.com/ was a nice try but they were not open to outsiders and did not have the backing from the insiders.

            The new one that I like a lot now is http://www.openscholar.org.uk/ That is the one to get behind right now. They have all the right ideas and attitudes.

            Hi Philip,

            I love your article and gave it the "10" it deserves. You've brought a lot of vital concepts to the fore, and I hope that you win the contest because of it. I hope that open peer review becomes standard practice someday, for so many reasons, and because it really could save the world. All the best!

            Warmly,

            Aaron

            Dear Philip

            Your essay is well written and organized. Your topic is well developed and controversial. Overall, I agree with some of parts of your essay, I just would like to express a couple of disagreements.

            First, I do not think changing the peer-review process is an important factor that will steer the future. High quality research will always prevail over bad quality research no matter what judging process we adopt. Bias and subjective opinions are intrinsic human characteristics that cannot be eliminated. We see this everywhere.

            Second, I think that the present peer-review system is the most solid. Science has a reputation gained over some centuries and it will not jeopardize it by changing its peer-review process. Your proposal, specially principle 3) will reduce the quality of research. And we see this in your repository. On average the quality of research published in vixra is inferior when compared to that one published in arxiv. Arxiv's policies (such as endorsement) guarantee a minimum of quality in research because most people are experts in their fields. Manuscripts that do not meet the minimum quality standards should be rejected. By contrast, in vixra, one can find many articles with very poor quality. In my opinion this is the reason vixra is not well seen in the academy. This is something I regret you do not discuss in your essay.

            Likewise, traditional journals vs open-access journals. The average quality of research published in traditional journals is far superior than that one published in open-access journals where as long as you pay the publication fee, your manuscript will be published even without a peer-review process. In my opinion open-access journals has gained a negative reputation due to their unethical practices. If these practices continue, my prediction is that they will all disappear by the end of the decade.

            Also regarding your third principle, if I do research in a field, I would like to be criticized by someone who knows about that topic but not by a layman who doesn't know the rudiments. Just in the same way, I would not criticize a musician for playing an instrument that I do not even know how to play. One can only criticize something if one has enough knowledge about it.

            Exams are filters to select the best for a given activity. It is not a method of suppression. What you call suppression, I would call it filtering in favor of higher quality in research.

            You: Wikipedia is a good example of a system that allows anyone to contribute.

            I wish this were true...

            Anyway. I would like to take this opportunity to invite you to read and comment on my thread.

            Best Regards

            Israel

              I think the best way to favour expertise in the reviews is to weight peoples opinions according to how well they themselves score in their own work on similar subjects. It should be a bit like the Google ranking system. Making that work well is difficult but picking experts by hand introduces unwanted bias into the system and should be avoided.

              I have not thought about coding biases into RDF/OWL. It is an intriguing idea.

              People studying the effect of cognitive bias in finance have looked at why it happens and when it can be an advantage. the answers are complicated and I am no expert, but in part it is just simpler to think that way. It may have evolved before we had the ability to perform more logical thinking. Sometimes it does work out OK, but often it does not. A lot of money has been lost by banks due to bad bias and the effect on the impact of science is liekly to be similar.

              I disagree that academics matter less than businessmen. Businesses have short term goals to make money. Academic research aims to solve longterm problems for the common good. Big pharam do not do much research into new antibiotics because it is not cost effective. Finding cures for rare diseases does not make money. More money is made by finding tablets that alleviate hay fever and dandruff and they make even more money if they just treat the symptoms temporarily rather than curing it. Businesses are good at improving technology once the basic principles are known. Academics are needed to make the important breakthroughs.