A signal is a physical event that conveys meaning. A ring of my phone, for instance, is a signal that means that somebody is calling. When I hear it, I understand its meaning and I may reach the phone and answer. Carlo Rovelli 2017
Does it covey meaning or is meaning produced from the sound signal on arrival? There is no labelled attached to the sound waves that has its meaning. The information is only what it is. That could be, as examples, a pattern, a structure or a simple physical characteristic such as a frequency of light or frequency of sound. Only if the means to produce the meaning exist is that, which is transmitted, meaningful. That red means stop must be learned before it has that meaning. Stop is not transmitted but the red frequency light is. Likewise, DNA is just a chemical. The protein product is the meaning, that doesn't exist until it is produced. It would probably be better if we stopped saying meaning is transmitted or conveyed and say instead meaning is translated, extracted or produced, only the carrier of the information is transmitted.
What distinguishes its being a signal, from its being a simple link in a physical causation chain? Carlo Rovelli 2017
I think that is a good question. I also think that is a person/people deciding to classify it as a signal because there is clearly transmission happening and specific (receipt)-response correlation. There are very many specific chemicals in biology that are considered to be signals; that bind with specific receptors causing recognized effects. Which works against your next point that the carrier could be different. While in some situations that is true, any buzzer or bell could call an assistant, and in other situations such as 'finely tuned' biochemistry it is not.
Thanks for a thought provoking, well written presentation.