Greetings Professor Josephson,
I enjoyed your essay, in its final form, as I did the draft I had the privilege to see before you posted this. You do address the question of what is fundamental in Physics, and you do it in a most unique and novel way. I'm glad I was introduced to your recent work via the talk you gave at the Elche campus of UMH (Universidad Miguel Hernandez) for FFP15 - because this gave me a lot more time to consider your novel ideas, and to let the ramifications sink in.
I will admit also here that my initial reaction was a naive impulse similar to Jack's, that I was put off by your terminology, but that I could convey some aspects of your message to Physics folks better - by casting it in the language of quantum mechanics. I inform the readers here that in my e-mail to you, Brian, I referenced the paper "There are no Quantum Jumps, nor are there Particles!" by H.D. Zeh where quantum information in the wavefunction is more fundamental than material reality.
But you were kind to point out the differences in the pictures suggested by decoherence theory and biosemiotics, and how that relates to your central thesis that meaning is fundamental. What you are talking about is a shift of emphasis beyond the framework Jack Sarfatti uses to explain how consciousness arises. After reading the paper with Shimansky he posted above; I see that he has shown there is something worthwhile to investigate, but is making excessive claims as to its validity or universality - given the level of evidence or proof offered.
I like what you have done here Brian, and I don't think you are making any excessive statements that would prompt me to exclude your ideas from careful consideration.
All the Best, JJDAttachment #1: 1_no-quantum-jumps.pdf