Dear Professor Josephson,
I am interested in your work presented here, also because I have my own, scientifically rigorous arguments in favour of the probable existence (necessity) of "other", biologically active levels of reality, not (yet) directly observable, but ontologically real. And I obtain this conclusion with the help of extended (reality-based and causally complete) mathematics of "unreduced dynamic complexity", corresponding to the description at the end of your essay abstract. You can find some major points in my essay here, with much more details in references therein. This is to say that the necessary mathematical framework may already exist, with clear signs of its efficiency. And what's interesting, it is the same one that helps to clarify "quantum mysteries" and other accumulated "contradictions" of standard science framework at "usual" fundamental levels of physical reality.