Hi Ian,
Thank you for a wonderfully written essay. I enjoyed it and I am largely in agreement with your conclusion, particularly when you wrote ``The fact remains that in order to say we comprehend some element of the universe we must necessarily obtain some information about that element. But obtaining that information is a physical process that necessarily has a context which constrains the nature of that information; the very act of acquiring information shapes the information acquired''.
This is an excellent point and the principle of comprehensibility is certainly a reflection of the physical limitations handed down by the uncertainty principle. As you point out, if the context of the questions being asked don't agree because we choose two incompatiable measurements---say x and p---then their is a fundamental limit to the comprehension we can achieve.
You then moved onto the price about the price of comprehension which fundamentally boils down to errors arising due to incompatible measurements. As you point out, if I'm computing pi to 50 trillion decimal places using two different algorithms, then surely they will reach different conclusions if they are not identical.
The uncertainty principle is certainly the fundamental limit of your essay, as it it in contextuality. If you ask an incomprehensible question, then it requires an infinite amount of energy to extract all the information about a particular variable. That is, localising your particles position does requires that you infinitely squeeze along p.
I largely agree with you and your essay and wrote a very similar essay focusing on the limits of computation, although focused from the perspective of open systems and dissipation---the errors arising from incomprehensible questions if you like---titled noisy machines. I hope you get a chance to take a look!
Well done on the great essay! I really enjoyed it!
Cheers,
Michael