Dear Ian,
"Why is the Universe so comprehensible?" A great topic to which you have written a most stimulating essay.
I think our world is comprehensible because humans are good at searching out and then explaining patterns. First in natural science, then in our own creation - mathematics. As our science progressed, some of the patterns, or our deductions about them became established as our principles or laws - especially where symmetry was involved.
I believe, like Einstein, that `comprehensibility' means a scientific understanding of the universe's functional composition. In my essay I cover how the 3 Un's have impinged on my thinking as I work towards my goal of 'Structural Physics'.
If a condition of comprehensibility is one of measurement, and as you quoted "Feynman once famously said, if something disagrees with experiment then it's wrong", then isn't defining the experiment and its measurement in a truth-conditional way extremely important. Some might argue that is where EPR experiments have come unstuck. Part of the price of comprehensibility is the way we design our experiments.
On another thought-line, you stated: "Markus Muller recently constructed a self-consistent theory in which an objective external world emerges from more fundamental observer states." Isn't this similar in some way to applying Susskind and 't Hooft's idea of a holographic black hole event horizon to the Universe through multiple observer states? After all, Muller thinks the link between entropy and information remains, possibly leading to a holographic principle.
Thanks for your essay as it has extended the boundaries of my thinking.
Lockie Cresswell